April 29, 2019, Medical News Bulletin
Small cell carcinoma accounts for about 0.1% of ovarian cancer cases with reported long-term survival rates of 33% when the disease is diagnosed at an early stage. Of these, about two-thirds of women with small cell carcinoma of the ovaries have hypercalcemia (SCCOHT — small cell carcinoma of the ovary, hypercalcemic type). Researchers discovered that inhibition of certain enzymes called cyclin-dependent kinases 4 and 6 (CDK4/6) blocked the growth of SCCOHT cancer cells.
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