December 21, 2018, MedPage Today  

Use of vaginal estrogen wasn't tied to increased cardiovascular or cancer risks, according to a new study.

Looking at postmenopausal women who participated in the Nurses' Health Study, vaginal estrogen use in women with or without an intact uterus was not associated with any increased risks of several cancers or cardiovascular outcomes over an 18-year follow-up period, reported JoAnn E. Manson, MD, DrPH, of Brigham and Women's Hospital in Boston, and colleagues.

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